Difference between revisions of "Sertraline-bupropion"
From Psychiatrienet
| Line 3: | Line 3: | ||
| to = bupropion | | to = bupropion | ||
| stop = | | stop = | ||
| + | {{stopSertraline}} | ||
* '''Before day 1:''' Gradually reduce dosage of sertraline to a maximum of 50 mg/ day, when this dosage is > 50 mg/day. | * '''Before day 1:''' Gradually reduce dosage of sertraline to a maximum of 50 mg/ day, when this dosage is > 50 mg/day. | ||
* '''Day 1:''' Reduce dosage of sertraline to a dosage of 25 mg/ day | * '''Day 1:''' Reduce dosage of sertraline to a dosage of 25 mg/ day | ||
| Line 9: | Line 10: | ||
| start = | | start = | ||
| − | * '''Day | + | * '''Day 15:''' Start administration of bupropion in a normal dosage of 150 mg/day for one week. |
| − | * '''Day | + | * '''Day 23:''' if necessary gradually increase dosage of bupropion to target dose. |
|info= | |info= | ||
| − | {{ | + | {{SSRI14d}} |
}} | }} | ||
Revision as of 14:08, 21 October 2015
| ||||||||||||||||||||||||||||
| ||||||||||||||||||||||||||||
Switch medication from sertraline to bupropion.[1] [2]
Stop sertraline - Before day 1: Gradually reduce dosage of sertraline to a maximum of 50 mg/ day, when this dosage is > 50 mg/day.
- Day 1: Reduce dosage of sertraline to a dosage of 25 mg/ day
- Day 8: Stop administration of sertraline
- Before day 1: Gradually reduce dosage of sertraline to a maximum of 50 mg/ day, when this dosage is > 50 mg/day.
- Day 1: Reduce dosage of sertraline to a dosage of 25 mg/ day
- Day 8: Stop administration of sertraline
Start bupropion- Day 15: Start administration of bupropion in a normal dosage of 150 mg/day for one week.
- Day 23: if necessary gradually increase dosage of bupropion to target dose.
More information- The reduction of the SSRI doses in 7-14 days could cause emotional instability, headache and flu-like symptoms. One could extend this period.
- ↑ Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
- ↑ Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
The editors of psychiatrienet.nl take the greatest care to provide up-to-date and accurate information on this site. Nevertheless, mistakes and omissions cannot be entirely excluded. No rights devolve from the information provided. The editors and other providers of information to this site accept no responsibility for the content of this site or for the information provided therein; neither do they accept responsibility for possible damages which may derive from the use of the information on this site or from the linked sites. The editorial board accepts no responsibility for the content of the (linked) sites, for access to them, or for the products and services on these sites, nor for the occurrence of errors, viruses, and/or disruptions in service.
