Difference between revisions of "Nortriptyline-moclobemide"
From Psychiatrienet
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| to = moclobemide | | to = moclobemide | ||
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| + | * '''Before day 0:''' gradually reduce dosage of nortriptyline to a maximum of 50 mg/ day, when this dosage is > 50 mg/day. | ||
| + | * '''Day 1-3:''' reduce dosage of nortriptyline to 25 mg/day. | ||
| + | * '''Day 4-7:''' reduce dosage of nortriptyline to 10 mg/day. | ||
| + | * '''Day 8:''' stop administration of nortriptyline. | ||
| + | | start = | ||
| + | * '''Day 8-14:''' a wash-out period of one week is necessary. | ||
| + | * '''Day 15:''' start administration of moclobemide in a dosage of 150 mg/day. | ||
| + | * '''Day 18:''' increase dosage of moclobemide to 300 mg/day.}} | ||
Revision as of 08:04, 6 May 2009
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Switch medication from nortriptyline to moclobemide.[1] [2]
Stop nortriptyline - Before day 0: gradually reduce dosage of nortriptyline to a maximum of 50 mg/ day, when this dosage is > 50 mg/day.
- Day 1-3: reduce dosage of nortriptyline to 25 mg/day.
- Day 4-7: reduce dosage of nortriptyline to 10 mg/day.
- Day 8: stop administration of nortriptyline.
Start moclobemide- Day 8-14: a wash-out period of one week is necessary.
- Day 15: start administration of moclobemide in a dosage of 150 mg/day.
- Day 18: increase dosage of moclobemide to 300 mg/day.
- ↑ Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
- ↑ Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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