| to = agomelatine
| stop =
{{stopVenlafaxine}}
| start =
* '''Day 1:''' simultaneously start administration of agomelatine in a dosage of 25 mg/day. * '''Day 8:''' continue administration of agomelatine. If necessary, increase dosage of agomelatine to 50 mg/day.<ref name="agoswitch"> {{Pubmed|20196187| info = * Venlafaxine stops the metabolism McAllister-Williams RH et al. The use of antidepressants in clinical practice: focus on agomelatine via CYP1A2 . Hum Psychopharmacol. 2010 Mar 1;25(90%2) and via CYP2C9:95-102}}</2C19 (10%).ref>}}