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{{stopVortioxetine}}
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* '''Day 8-21:''' a wash-out period of two weeks is necessary.<ref name="vortiswitch"> {{Pubmed|24570588 |Katona et al. New generation multi-modal antidepressants: focus on vortioxetine for major depressive disorder. 2014 2014 Feb 19;10:349-54}}</ref> <ref name="informatorium">{{KNMP|vortioxetine}}</ref>
* '''Day 22:''' Start administration of tranylcypromine in low dosage of 20 mg/day for one week.
* '''Day 29:''' after this week the dosage of tranylcypromine can be increased if necessary.
