Difference between revisions of "Duloxetine-moclobemide"

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* '''Day 0:''' gradually reduce dosage of duloxetine to a maximum of 30 mg/ day. When a dosage of 30 mg/day is reached, stop administration.
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{{Generaldecrease25p3d}}
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A wash-out period of one week is necessary.
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* '''Day 1-7:''' wash-out period
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|cave=
* '''Day 8:''' start administration of moclobemide is a normal dosage of 300 mg/day.
 
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{{caveSS}}
 
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Latest revision as of 13:34, 16 June 2016

Duloxetine
Type Antidepressant
Group SNRI
links
Medscape Duloxetine
PubChem 60835
PubMed Duloxetine
Kompas (Dutch) Duloxetine
Wikipedia Duloxetine
Moclobemide
Type Antidepressant
Group MAO-I
links
Medscape Moclobemide
PubChem 4235
PubMed Moclobemide
Kompas (Dutch) Moclobemide
Wikipedia Moclobemide

Switch medication from duloxetine to moclobemide.[1] [2]

Nietinrijdenbord.png Stop duloxetine
  • Decrease with about 25% of original dose every 3 days
  • Stop and wait 7 days for washout
Eenrichtingbord.png Start moclobemide
  • Start at the first day after the washout period with about 25% of target dose.
Letopbord.png Cave


  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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