Difference between revisions of "Partial antagonist-Rest AP"
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Latest revision as of 15:33, 29 October 2021
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Switch medication from Partial antagonist to Rest AP.[1]
[2]
Partial antagonist is a collection of antipsychotic drugs having similar properties with respect to switching. A switch to member of the 'partial antagonist' group from anotherdrug should be read as partial antagonist-anotherdrug. Similarly, a switch from a member of the 'partial antagonist' group to anotherdrug should be read as anotherdrug-partial antagonist.
Stop Partial antagonist - Day 1-21: Continue drug at usual dose
- Day 22: Stop drug
Start Rest AP- Day 1-4: approx. 25% of target dose
- Day 5-8: approx. 50% of target dose
- Day 9-12: approx. 75% of target dose
- Day 13: target dose
- Day 28: Reevaluate dose, if necessary adjust dose
More information
— Partial antagonist — Rest AP
- ↑ Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
- ↑ Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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