Difference between revisions of "Partial antagonist-Partial antagonist"

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Latest revision as of 16:01, 29 October 2021

Partial antagonist

Aripiprazole
Brexpiprazole
Cariprazine

Partial antagonist

Aripiprazole
Brexpiprazole
Cariprazine

Switch medication from Partial antagonist to Partial antagonist.[1] [2]
Partial antagonist is a collection of antipsychotic drugs having similar properties with respect to switching. A switch to member of the 'partial antagonist' group from anotherdrug should be read as partial antagonist-anotherdrug. Similarly, a switch from a member of the 'partial antagonist' group to anotherdrug should be read as anotherdrug-partial antagonist.

Nietinrijdenbord.png Stop Partial antagonist
  • Day 1-4: approx. 75% of initial dose
  • Day 5-8: approx. 50% of initial dose
  • Day 9-12: approx. 25% of initial dose
  • Day 13: stop
Eenrichtingbord.png Start Partial antagonist
  • Day 1-3: start 50% of target dose
  • Day 4-7: target dose
Infobord.png More information
PartialtoPartial.jpg
Nietinrijdenbord.png — Partial antagonist
Eenrichtingbord.png — Partial antagonist


  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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