Difference between revisions of "Paliperidone ER-Partial agonist"
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Revision as of 16:14, 18 March 2022
* This switch is intended for paliperidone long acting (Xeplion®, 30 days)
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Switch medication from Haloperidol_LA to Partial agonist.[4]
[5]
Partial agonist is a collection of antipsychotic drugs having similar properties with respect to switching. A switch to member of the 'partial agonist' group from anotherdrug should be read as partial agonist-anotherdrug. Similarly, a switch from a member of the 'partial agonist' group to anotherdrug should be read as anotherdrug-partial agonist.
Stop Haloperidol_LA - Day 1: Last depot injection
Start Partial agonist- Start drug at target dose on the day you would normally have injected the next depot.
More information- During this switch you could monitor ECG, especially in patients prone to QT-conduction problems.
- There is a possibility of QT interval prolongation.[6]
— Haloperidol_LA — Partial agonist
- ↑ WHO Collaborating Centre for Drug Statistics Methodology ATC=N05AD01
- ↑ 2.0 2.1 The Lundbeck Institute; Psychotropics; Terminal Plasma Half-lives
- ↑ 3.0 3.1 Farmacotherapeutisch Kompas; Inleidende Tekst Antipsychotica (dutch)
- ↑ Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
- ↑ Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
- ↑ Stöllberger C, Huber JO, Finsterer J, Antipsychotic drugs and QT prolongation. Int Clin Psychopharmacol. 2005 Sep;20(5):243-51.
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