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Fluoxetine-trazodone

251 bytes removed, 17:29, 24 February 2023
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| to = trazodone
| stop =
* '''Before day 1:'''gradually reduce dosage of fluoxetine to a maximum of 20 mg/ day, when this dosage is > 20 mg/day. * '''Before day 1:'''When a dosage of 20 mg/day is reached, stop administration.{{stopfluox}}
| start =
* No wash-out period is needed. * Start trazodone the next day in normal dosage of 150 mg/day.* If necessary, increase the dosage of trazodone to a maximum of 400 mg/day.{{startnafluox}}
| info =
{{longt1/2fluvox}}* Fluoxetine slows the metabolism of trazodone via CYP2D6, so caution is necessary for at least four weeks.* {{theorSS}}* Safe target dose of trazodon as antidepressant = 150 mg }}

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