| to = trazodone
| stop =
* '''Before day 1:'''gradually reduce dosage of fluoxetine to a maximum of 20 mg/ day, when this dosage is > 20 mg/day. * '''Day 1:'''When a dosage of 20 mg/day is reached, stop administration.{{stopfluox}}
| start =
* '''Day 1-21:''' A wash-out period is needed. * '''Day 22:'''Start trazodone in a dosage of 100-150 mg/day.* '''After day 28 :'''If necessary, increase gradually the dosage of trazodone to a maximum of 400 mg/day.{{startnafluox}}
| info =
{{longt1/2fluvox}}* Fluoxetine slows the metabolism of trazodone via CYP2D6, so caution is necessary for at least four weeks.}}* {{therSStheorSS}}* Safe target dose of trazodon as antidepressant = 150 mg
}}
