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Sertraline-citalopram

464 bytes removed, 17:37, 24 February 2023
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{{Drugswitch
| from = sertraline
| to = nortriptylinecitalopram| stop = * '''Day 0:''' gradually reduce dosage of sertraline to a maximum of 50 mg/day when this dosage is > 50 mg/day. * '''Day 1:''' reduce dosage of sertraline to a maximum of 25 mg/day. {{StopSSRI,SNRI}}| start = {{StartAntidepressant}}Caution is necessary.| info =* '''Day 1:''' simultaneously start administration of nortriptyline in a low dosage of 25 Safe target dose citalopram = 20 mg/day. * '''Day 8:''' stop administration of sertraline and only continue administration of nortriptyline in a dosage of 50 mg/day.{{possiblestartstop}}* "Start low, go slow" is not required, but caution is necessary.| info = {{theorSS}}* Sertraline dose-dependently slows the metabolism of amitriptyline via CYP2D6. }}

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