| to = sertraline
| stop =
* '''Before day 0:''' gradually reduce dosage of amitriptyline to a maximum of 25-50 mg/day.{{TCAdecrease25p3d}}* '''Day 1:''' reduce dosage of amitriptyline to 25 mg/day.* '''Day 3:''' reduce dosage of amitriptyline to 10 mg/day.| start = {{StartAntidepressant}}| start info = * '''Day 1:''' simultaneously start administration of Safe target dose sertraline in a normal dosage of = 50 mg/day.* '''Day 8:''' stop administration of amitriptyline and continue administration of sertraline.| info = * Occurrence of serotonin syndrome is theoretically possible, so caution is necessary.}}