Difference between revisions of "Maprotiline-fluvoxamine"

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| to = fluvoxamine
 
| to = fluvoxamine
 
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* '''Before day 0:''' gradually reduce dosage of maprotiline to a maximum of 75 mg/day.
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{{TCAdecrease25p3d}}
* '''Day 1:''' reduce dosage of maprotiline to 50 mg/day.
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| start = {{StartAntidepressant}}
* '''Day 3:''' reduce dosage of maprotiline to 25 mg/day.
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| info =
| start =  
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* Safe target dose fluvoxamine = 100 mg
* '''Day 1:''' simultaneously start administration of fluvoxamine in a normal dosage of 50 mg/day.
 
* '''Day 8:''' stop administration of maprotiline and continue administration of fluvoxamine in a dosage of 50-100 mg/day.
 
| info =
 
 
 
 
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Latest revision as of 11:47, 30 June 2023

Maprotiline
Type Antidepressant
Group NRI
links
Medscape Maprotiline
PubChem 4011
PubMed Maprotiline
Kompas (Dutch) Maprotiline
Wikipedia Maprotiline
Fluvoxamine
Type Antidepressant
Group SSRI
links
Medscape Fluvoxamine
PubChem 5324346
PubMed Fluvoxamine
Kompas (Dutch) Fluvoxamine
Wikipedia Fluvoxamine

Switch medication from maprotiline to fluvoxamine.[1] [2]

Nietinrijdenbord.png Stop maprotiline
  • Day 1: Decrease with about 25% of the original dose per 3 days.
Eenrichtingbord.png Start fluvoxamine
  • Day 1: Start with 50% of the target dose
  • Day 8: Increase dose to 100% of the target dose
  • Day 9 and after: Gradually increase dose as necessary
Infobord.png More information
  • Safe target dose fluvoxamine = 100 mg
  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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