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| to = vortioxetine
| stop =
{{TCAdecrease25p3d}}| stop start = * '''Before day 1:''' gradually reduce dosage of maprotiline to a maximum of 75 mg/day.* '''Day 1:''' reduce dosage of maprotiline to 50 mg/day.* '''Day 8:''' reduce dosage of maprotiline to 25 mg/day.* '''Day 15:''' stop dosage of maprotiline.{{StartAntidepressant}}| start info = * A wash-out period is not necessary.* '''Day 15:''' start administration of Safe target dose vortioxetine in a dosage of = 10 mg/day.
}}