| to = maprotiline
| stop =
* '''Day 0:''' gradually reduce dosage of fluvoxamine to a maximum of 50 mg/ day when this dosage is > 50 mg/day. * '''Day 1:''' reduce dosage of fluvoxamine to a maximum of 25 mg/day. {{TCAdecrease25p3d}}
| start =
Caution is necessary.* '''Day 1:''' simultaneously start administration of maprotiline in a low dosage of 25-75 mg/day.* '''Day 8:''' stop administration of fluvoxamine and continue administration of maprotiline. If necessary, increase dosage of maprotiline.{{TCAincrease25p3d}}| info = * Fluvoxamine slows the metabolism of imipramine via CYP1A2 and CYP2D6.{{TCAplasmalevelmonitoring}}* "Start low, go slow" is not required, but caution is necessary.}}