Difference between revisions of "Nortriptyline-amitriptyline"

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{{Drugswitch  
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{{Drugswitch
 
| from = nortriptyline
 
| from = nortriptyline
| to = amitriptyline
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| to = amitriptyline  
 
| stop =  
 
| stop =  
{{downNortriptyline}}
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{{TCAdecrease25p3d}}
 
| start =  
 
| start =  
 
* No wash-out period is needed.  
 
* No wash-out period is needed.  
* ''' Day 9: '' start administration of amitriptyline in a normal dosage of 50-100 mg/day.
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{{TCAincrease25p3d}}
 
| info =
 
| info =
* {{TCAantichol}}
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{{TCAplasmalevelmonitoring}}
 
}}
 
}}

Latest revision as of 16:08, 30 June 2023

Nortriptyline
Type Antidepressant
Group TCA
links
Medscape Nortriptyline
PubChem 4543
PubMed Nortriptyline
Kompas (Dutch) Nortriptyline
Wikipedia Nortriptyline
Amitriptyline
Type Antidepressant
Group TCA
links
ATC-code N06AA09
Medscape Amitriptyline
PubChem 2160
PubMed Amitriptyline
Kompas (Dutch) Amitriptyline
Wikipedia Amitriptyline

Switch medication from nortriptyline to amitriptyline.[1] [2]

Nietinrijdenbord.png Stop nortriptyline
  • Day 1: Decrease with about 25% of the original dose per 3 days.
Eenrichtingbord.png Start amitriptyline
  • No wash-out period is needed.
  • Day 1: Increase with about 25% of target dose per 3 days.
Infobord.png More information
  • Plasma monitoring for TCA's is advisable, because of plasma-reponse relations, genetic polymorphism and under or overdosing.[3]
  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
  3. (dutch) monografie.org tricyclische-antidepressiva
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