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Bupropion-amitriptyline

253 bytes removed, 11:56, 4 August 2023
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| to = amitriptyline
| stop =
* '''Before day 1:''' Gradually reduce dosage of bupropion to a maximum of 150 mg/ day.* '''Day 1:''' Stop administration of bupropion{{StopBupropion}}
| start =
* '''Day 1-3:''' start administration of Start amitriptyline in with a low dosage of 25 mg/day.* '''Day 48:''' increase dosage of amitriptyline to a dosage of 50 mg/day and continue slowly increasing the dosage depending on the condition of the patient. 
| info =
* Bupropion slows the metabolism of amitriptyline via CYP2D6.
* Caution is necessary at the start of administration of amitriptyline.
* {{RiskSeizureBupropionTCA}}
* {{TCAplasmalevelmonitoring}}
}}
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