Difference between revisions of "Bupropion-fluvoxamine"

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| to = fluvoxamine
 
| to = fluvoxamine
 
| stop =  
 
| stop =  
{{StopBupropion1}}
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{{StopBupropion}}
 
| start =  
 
| start =  
* ''' Day 2: ''' Start fluvoxamine in normal dosage of 50 mg/day.
+
* ''' Day 1: ''' Start fluvoxamine in normal dosage of 50 mg/day.
* ''' After 3 weeks:''' If necessary increase dosage gradually to 100-300 mg/day
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* ''' Day 4:''' If necessary, gradually increase dosage  
 
| info =   
 
| info =   
* No wash-out period is needed.
 
* Bupropion and its metabolites have long elimination times, so plasma concentrations will reduce gradually.
 
{{lowlevels}}
 
 
}}
 
}}

Latest revision as of 11:12, 4 August 2023

Bupropion
Type Antidepressant
Group other
links
ATC-code N06AX12
Medscape Bupropion
PubChem 444
PubMed Bupropion
Kompas (Dutch) Bupropion
Wikipedia Bupropion
Fluvoxamine
Type Antidepressant
Group SSRI
links
Medscape Fluvoxamine
PubChem 5324346
PubMed Fluvoxamine
Kompas (Dutch) Fluvoxamine
Wikipedia Fluvoxamine

Switch medication from bupropion to fluvoxamine.[1] [2]

Nietinrijdenbord.png Stop bupropion
  • Day 1: Stop bupropion.
  • bupropion can be stopped abruptly for every dosage.[3]
Eenrichtingbord.png Start fluvoxamine
  • Day 1: Start fluvoxamine in normal dosage of 50 mg/day.
  • Day 4: If necessary, gradually increase dosage


  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
  3. Multidisciplinair document Afbouwen Overige Antidepressiva 2023
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