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Bupropion-trazodone

185 bytes removed, 12:41, 4 August 2023
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| to = trazodone
| stop =
* Gradually reduce dosage of bupropion to a maximum of 150 mg/day. * When a dosage of 150 mg/day is reached, stop administration.{{stopBupropion}}
| start =
* ''' Day 1: ''' Start trazodone the same day in with a normal dosage of 100-150 75 mg/day.* ''' Day 8: ''' If necessary, gradually increase dosage
| info =
* Bupropion and its metabolites have long elimination times, so plasma concentrations will reduce gradually.
* Bupropion and its metabolites slow the metabolism of trazodone by CYP2D6.
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