Difference between revisions of "Mirtazapine-venlafaxine"

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| from = mirtazapine  
 
| from = mirtazapine  
 
| to = venlafaxine  
 
| to = venlafaxine  
| stop =  
+
| stop = {{StopSSRI,SNRI}}
* '''Day 1:''' reduce dosage of mirtazapine to a maximum of 30 mg/day.
+
| start = {{StartAntidepressant}}
* '''Day 7:''' reduce to 15 mg/day.
+
| info =
* '''Day 14:''' stop administration.
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* Safe target dose venlafaxine = 75 mg
 
+
* {{theorSS}}
| start =  
+
}}
* '''Day 14:''' start venlafaxine in a normal dosage of 37, mg or 75 mg (slow realease)/day.}}
 

Latest revision as of 17:17, 24 February 2023

Mirtazapine
Type Antidepressant
Group other
links
Medscape Mirtazapine
PubChem 4205
PubMed Mirtazapine
Kompas (Dutch) Mirtazapine
Wikipedia Mirtazapine
Venlafaxine
Type Antidepressant
Group SNRI
links
Medscape Venlafaxine
PubChem 5656
PubMed Venlafaxine
Kompas (Dutch) Venlafaxine
Wikipedia Venlafaxine

Switch medication from mirtazapine to venlafaxine.[1] [2]

Nietinrijdenbord.png Stop mirtazapine
  • Day 1: Decrease dose to 50%
  • Day 8: Stop
Eenrichtingbord.png Start venlafaxine
  • Day 1: Start with 50% of the target dose
  • Day 8: Increase dose to 100% of the target dose
  • Day 9 and after: Gradually increase dose as necessary
Infobord.png More information
  • Safe target dose venlafaxine = 75 mg
  • Occurrence of the serotonin syndrome is not likely, but theoretically possible, so caution is necessary.
  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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