Difference between revisions of "Olanzapine"

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{{Drug
 
{{Drug
 
| name = Olanzapine
 
| name = Olanzapine
| group = Atypical AP
+
| group = atypical AP
 +
| type = antipsychotic
 +
| otheruse = moodstabilizer
 
| pubchem = 4585
 
| pubchem = 4585
| half =
 
 
| medscape = 1644
 
| medscape = 1644
| emea = Olanzapine
+
| emea = zyprexa
| therapy1 =  
+
| ATC = N05AH03
| therapyid1 =  
+
| CAS = 132539-06-1
| therapyname1 =  
+
| ChemSpiderID = 10442212
| therapy2 =  
+
| drugbank = APRD00138
| therapyid2 =
+
| drugscom = olanzapine
| therapyname2 =  
 
 
| ftk = olanzapine
 
| ftk = olanzapine
| othername1 =  
+
| metabolization = * Olanzapine is principally metabolized by CYP1A2 and CYP2D6.
| other1 =  
+
| start =  
| otherid1 =  
+
| stop =  
| other2 =  
+
| equivalent = 0.4
| otherid2 =  
+
| equivalent_ref = <ref>Woods SW Chlorpromazine equivalent doses for the newer atypical antipsychotics; ''J Clin Psychiatry'' 2003;'''64''':663-667</ref>
| othername2 =  
+
| comparison = haloperidol
| type = Antipsychotic
+
<!--
 +
| avail = unknown
 +
-->
 +
| halflife = 32-52
 +
| halflife_ref = <ref name="informatorium">{{KNMP|olanzapine}}</ref>
 +
| ct = 11
 +
| ct_ref = <ref name="informatorium" />
 +
| administration = oral
 +
| dose = 2.5-20
 +
| dose_ref = <ref name="informatorium" />
 +
| DDD = 30
 +
| DDD_ref = <ref name="informatorium" />
 +
| ctox = 100
 +
| ctox_ref = {{FTK-TOX}}
 +
| <includeonly>| isswitch = 1 </includeonly>
 
}}
 
}}
<noinclude>[[Category:Drug]]</noinclude>
 

Latest revision as of 00:20, 27 April 2010

Olanzapine
Type antipsychotic
Group atypical AP
Other use moodstabilizer
links
ATC-code N05AH03
Medscape Olanzapine
EMEA zyprexa
PubChem 4585
PubMed Olanzapine
Drugs.com olanzapine
Kompas (Dutch) Olanzapine
Wikipedia Olanzapine

"-52" can not be assigned to a declared number type with value 32.






Olanzapine is a antipsychotic in the group atypical AP. Olanzapine is also used as moodstabilizer.


Metabolization
  • Olanzapine is principally metabolized by CYP1A2 and CYP2D6.


  1. 1.0 1.1 1.2 1.3 KNMP; Informatorium Medicamentorum 2023; Monografie "olanzapine" (Dutch)
  2. Farmacotherapeutisch Kompas; Toxicologie (dutch)
  3. Woods SW Chlorpromazine equivalent doses for the newer atypical antipsychotics; J Clin Psychiatry 2003;64:663-667