Difference between revisions of "Sertraline-citalopram"

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| from = sertraline  
 
| from = sertraline  
 
| to = citalopram
 
| to = citalopram
| stop =  
+
| stop = {{StopSSRI,SNRI}}
* Gradually reduce dosage of sertraline to a maximum of 50 mg/ day, when this dosage is > 50 mg/day.
+
| start = {{StartAntidepressant}}
* When a dosage of 50 mg/day is reached, stop administration.
 
| start =  
 
* No wash-out period is needed.
 
* Start citalopram/escitalopram the next day in normal dosage of 20 mg/day, resp. 10 mg/day.
 
 
| info =
 
| info =
 +
* Safe target dose citalopram = 20 mg
 +
* {{possiblestartstop}}
 
* {{theorSS}}
 
* {{theorSS}}
 
}}
 
}}

Latest revision as of 16:37, 24 February 2023

Sertraline
Type Antidepressant
Group SSRI
links
Medscape Sertraline
PubChem 68617
PubMed Sertraline
Kompas (Dutch) Sertraline
Wikipedia Sertraline
Citalopram
Type Antidepressant
Group SSRI
links
ATC-code N06AB04
Medscape Citalopram
PubChem 2771
PubMed Citalopram
Kompas (Dutch) citalopram
Wikipedia citalopram

Switch medication from sertraline to citalopram.[1] [2]

Nietinrijdenbord.png Stop sertraline
  • Day 1: Decrease dose to 50%
  • Day 8: Stop
Eenrichtingbord.png Start citalopram
  • Day 1: Start with 50% of the target dose
  • Day 8: Increase dose to 100% of the target dose
  • Day 9 and after: Gradually increase dose as necessary
Infobord.png More information
  • Safe target dose citalopram = 20 mg
  • A start stop switch is possible, although withdrawal symptoms and/or side effects are more likely
  • Occurrence of the serotonin syndrome is not likely, but theoretically possible, so caution is necessary.
  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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