Difference between revisions of "Citalopram-mirtazapine"

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| from = citalopram  
 
| from = citalopram  
 
| to = mirtazapine  
 
| to = mirtazapine  
| stop =  
+
| stop = {{StopSSRI,SNRI}}
* '''Before day 0:''' gradually reduce dosage of citalopram/escitalopram to a maximum of 20 mg/ day resp. 10 mg/day, when this dosage is respectively > 20 mg/day and > 10 mg/day.
+
| start = {{StartAntidepressant}}
* '''Day 1:''' reduce dosage of citalopram/escitalopram to a maximum of 10 mg/ day resp. 5 mg/day.
+
| info =
| start =  
+
* Safe target dose mirtazapine = 15 mg
* '''Day 1:''' simultaneously start mirtazapine in a normal dosage of 15-30 mg/day.
 
* '''Day 8:''' stop administration of citalopram/escitalopram and continue administration of mirtazapine.
 
| info =  
 
* The same applies to [[escitalopram]].
 
 
}}
 
}}

Latest revision as of 15:26, 24 February 2023

Citalopram
Type Antidepressant
Group SSRI
links
ATC-code N06AB04
Medscape Citalopram
PubChem 2771
PubMed Citalopram
Kompas (Dutch) citalopram
Wikipedia citalopram
Mirtazapine
Type Antidepressant
Group other
links
Medscape Mirtazapine
PubChem 4205
PubMed Mirtazapine
Kompas (Dutch) Mirtazapine
Wikipedia Mirtazapine

Switch medication from citalopram to mirtazapine.[1] [2]

Nietinrijdenbord.png Stop citalopram
  • Day 1: Decrease dose to 50%
  • Day 8: Stop
Eenrichtingbord.png Start mirtazapine
  • Day 1: Start with 50% of the target dose
  • Day 8: Increase dose to 100% of the target dose
  • Day 9 and after: Gradually increase dose as necessary
Infobord.png More information
  • Safe target dose mirtazapine = 15 mg
  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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