Difference between revisions of "Risperidone"
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{{Drug | {{Drug | ||
| name = Risperidone | | name = Risperidone | ||
− | | group = | + | | group = atypical AP |
| type = antipsychotic | | type = antipsychotic | ||
− | | otheruse = | + | | otheruse = moodstabilizer |
| CAS = 106266-06-2 | | CAS = 106266-06-2 | ||
| ChemSpiderID = 4895 | | ChemSpiderID = 4895 | ||
Line 14: | Line 14: | ||
| ftk = risperidon | | ftk = risperidon | ||
| equivalent = 1 | | equivalent = 1 | ||
− | | equivalent_ref = <ref>Woods SW Chlorpromazine equivalent doses for the newer atypical antipsychotics ''J Clin Psychiatry'' 2003;'''64''':663-667</ref> | + | | equivalent_ref = <ref>{{pubmed|12823080|Woods SW; Chlorpromazine equivalent doses for the newer atypical antipsychotics ''J Clin Psychiatry'' 2003;'''64''':663-667}}</ref> |
| comparison = haloperidol | | comparison = haloperidol | ||
| avail = 70 | | avail = 70 | ||
| avail_ref = <ref name="informatorium">{{KNMP|risperidon}}</ref> | | avail_ref = <ref name="informatorium">{{KNMP|risperidon}}</ref> | ||
| halflife = 3 | | halflife = 3 | ||
− | | halflife_ref = <ref name=" | + | | halflife_ref = <ref name="pts">{{pts|1751}}</ref> |
| ct = 6 | | ct = 6 | ||
− | | ct_ref = <ref | + | | ct_ref = <ref name="pts" /> |
− | | administration = | + | | administration = O |
| dose = 0.25-4 | | dose = 0.25-4 | ||
| dose_ref = <ref name="informatorium" /> | | dose_ref = <ref name="informatorium" /> | ||
− | | DDD = | + | | DDD = 5 |
| metabolization = | | metabolization = | ||
− | * Risperidone is principally metabolized by CYP2D6 to an active metabolite. | + | * Risperidone is principally metabolized by CYP2D6 to an active metabolite 9-OH-risperidone (paliperidone). |
|<includeonly> isswitch = 1</includeonly> | |<includeonly> isswitch = 1</includeonly> | ||
}} | }} |
Latest revision as of 17:33, 29 June 2010
Risperidone | |||||||||||||||||
Type | antipsychotic | ||||||||||||||||
Group | atypical AP | ||||||||||||||||
Other use | moodstabilizer | ||||||||||||||||
links | |||||||||||||||||
ATC-code | N05AX08 | ||||||||||||||||
Medscape | Risperidone | ||||||||||||||||
PubChem | 5073 | ||||||||||||||||
PubMed | Risperidone | ||||||||||||||||
Drugs.com | risperidone | ||||||||||||||||
Kompas (Dutch) | Risperidone | ||||||||||||||||
Wikipedia | Risperidone | ||||||||||||||||
|
Risperidone is a antipsychotic in the group atypical AP. Risperidone is also used as moodstabilizer.
- Metabolization
- Risperidone is principally metabolized by CYP2D6 to an active metabolite 9-OH-risperidone (paliperidone).
- ↑ 1.0 1.1 KNMP; Informatorium Medicamentorum 2023; Monografie "risperidon" (Dutch)
- ↑ Woods SW; Chlorpromazine equivalent doses for the newer atypical antipsychotics J Clin Psychiatry 2003;64:663-667
- ↑ 3.0 3.1 The Lundbeck Institute; Psychotropics; Terminal Plasma Half-lives