Difference between revisions of "Moclobemide-tranylcypromine"

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* Gradually reduce dosage of moclobemide to a maximum of 300 mg/ day.
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* When a dosage of 300 mg/day is reached, stop administration.
 
 
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* '''Day 1-2:''' a wash-out period of two days is necessary.
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* '''Day 3:''' start tranylcypromine after this period in a normal dosage of 20 mg/day.}}
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Latest revision as of 14:41, 8 March 2024

Moclobemide
Type Antidepressant
Group MAO-I
links
Medscape Moclobemide
PubChem 4235
PubMed Moclobemide
Kompas (Dutch) Moclobemide
Wikipedia Moclobemide
Tranylcypromine
Type Antidepressant
Group MAO-I
links
Medscape Tranylcypromine
PubChem 5530
PubMed Tranylcypromine
Kompas (Dutch) Tranylcypromine
Wikipedia Tranylcypromine

Switch medication from moclobemide to tranylcypromine.[1] [2]

Nietinrijdenbord.png Stop moclobemide
  • Decrease with about 25% of original dose every 3 days
Eenrichtingbord.png Start tranylcypromine
  • Start tranylcypromine in a low dosage of 20 mg/day for one week.
  • After this week the dosage of tranylcypromine can be increased.
Infobord.png More information
  • No wash-out period is necessary
  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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