* '''Day 0:''' gradually reduce dosage of duloxetine to a maximum of 60 mg/ day.
* '''Day 1:''' reduce a dosage of 60 mg/day to 30 mg/day.
* '''Day 8:''' stop administration of duloxetine.
| start =
* '''Day 18:''' simultaneously start mirtazapine in a normal dosage of 15-30 mg/day.* '''Day 815:''' stop administration of duloxetine and continue with if necessary increase mirtazapine only. }}