| to = imipramine
| stop =
* '''Before day 1:''' gradually reduce dosage of mirtazapine to a maximum of 30 mg/ day.{{stopMirtazapine}}* '''Day 1:''' reduce a dosage of 30 mg/day to 15 mg/day.
| start =
No wash-out period is needed.{{Inc25p3d2}}* '''Day 1:''' simultaneously start Start administration of imipramine in a dosage of 25-75 mg/day. | info =* '''Day 8:''' stop administration of mirtazapine and continue administration of imipramine. If necessary, increase dosage of imipramineNo wash-out period is needed.
* Start low, go slow.
| info =
{{review}}
}}