Difference between revisions of "Bupropion-venlafaxine"

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* No wash-out period is needed.  
 
* No wash-out period is needed.  
* Start venlafaxine the next day in a normal dosage of 75 mg/day.
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* Start venlafaxine the next day in a normal dosage of 75 mg (slow release)/day.
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* Bupropion and its metabolites have long elimination times, so plasma concentrations will reduce gradually.}}
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Revision as of 07:58, 20 July 2009

Bupropion
Type Antidepressant
Group other
links
ATC-code N06AX12
Medscape Bupropion
PubChem 444
PubMed Bupropion
Kompas (Dutch) Bupropion
Wikipedia Bupropion
Venlafaxine
Type Antidepressant
Group SNRI
links
Medscape Venlafaxine
PubChem 5656
PubMed Venlafaxine
Kompas (Dutch) Venlafaxine
Wikipedia Venlafaxine

Switch medication from bupropion to venlafaxine.[1] [2]

Nietinrijdenbord.png Stop bupropion
  • Gradually reduce dosage of bupropion to a maximum of 150 mg/day.
  • When a dosage of 150 mg/day is reached, stop administration.
Eenrichtingbord.png Start venlafaxine
  • No wash-out period is needed.
  • Start venlafaxine the next day in a normal dosage of 75 mg (slow release)/day.


  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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