Difference between revisions of "Moclobemide-agomelatine"
From Psychiatrienet
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| − | * '''Day | + | * '''Day 8:''' start administration of agomelatine in a dosage of 25 mg/day. |
| − | * '''Day | + | * '''Day 15:''' if necessary, increase dosage of agomelatine to 50 mg/day. |
<ref name="agoswitch"> {{Pubmed|20196187|McAllister-Williams RH et al. The use of antidepressants in clinical practice: focus on agomelatine. Hum Psychopharmacol. 2010 Mar 1;25(2):95-102}}</ref> | <ref name="agoswitch"> {{Pubmed|20196187|McAllister-Williams RH et al. The use of antidepressants in clinical practice: focus on agomelatine. Hum Psychopharmacol. 2010 Mar 1;25(2):95-102}}</ref> | ||
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Revision as of 13:21, 14 October 2015
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Switch medication from moclobemide to agomelatine.[1] [2]
Stop moclobemide 
Start agomelatine- Day 8: start administration of agomelatine in a dosage of 25 mg/day.
- Day 15: if necessary, increase dosage of agomelatine to 50 mg/day.
More information- Because of short halve life of moclobemide after stopping, the next antidepressant can start next day.
- ↑ Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
- ↑ Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
- ↑ McAllister-Williams RH et al. The use of antidepressants in clinical practice: focus on agomelatine. Hum Psychopharmacol. 2010 Mar 1;25(2):95-102
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