Difference between revisions of "Escitalopram-maprotiline"

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| stop = {{StopEscitalopram}}
 
| stop = {{StopEscitalopram}}
 
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* '''Day 8:''' start administration of maprotiline in a normal dosage of 25 mg/day.
+
* '''Day 9:''' start administration of maprotiline in a normal dosage of 25 mg/day.
* '''Day 15:''' increase dosage of maprotiline.  
+
* '''Day 16:''' increase dosage of maprotiline.  
| info = {{review}}
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| info = {{theorSS}}
 
}}
 
}}

Revision as of 13:30, 28 October 2015

Escitalopram
Type Antidepressant
Group SSRI
links
Medscape Escitalopram
PubChem 10832572
PubMed Escitalopram
Kompas (Dutch) Escitalopram
Wikipedia Escitalopram
Maprotiline
Type Antidepressant
Group NRI
links
Medscape Maprotiline
PubChem 4011
PubMed Maprotiline
Kompas (Dutch) Maprotiline
Wikipedia Maprotiline

Switch medication from escitalopram to maprotiline.[1] [2]

Nietinrijdenbord.png Stop escitalopram
  • Before day 1: gradually reduce dosage of escitalopram to a maximum of 10 mg/day, when this dosage is >10 mg/day.
  • Day 1: reduce dosage of escitalopram to a maximum of 5 mg/day.
  • Day 8: stop administration of escitalopram.
Eenrichtingbord.png Start maprotiline
  • Day 9: start administration of maprotiline in a normal dosage of 25 mg/day.
  • Day 16: increase dosage of maprotiline.
Infobord.png More information

Occurrence of the serotonin syndrome is not likely, but theoretically possible, so caution is necessary.

  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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