Difference between revisions of "Doxepine-nortriptyline"

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| start =  
 
* No wash-out period is needed.  
 
* No wash-out period is needed.  
* ''' Day 9: ''' start administration of nortriptyline in a normal dosage of 50 mg/day.
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* {{TCAantichol}}
 
* {{TCAantichol}}
 
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Revision as of 12:47, 16 June 2016

Doxepin
Type antidepressant
Group TCA
links
ATC-code N06AA12
Medscape Doxepin
PubChem 3158
PubMed Doxepin
Drugs.com doxepin
Kompas (Dutch) Doxepin
Wikipedia Doxepin
Nortriptyline
Type Antidepressant
Group TCA
links
Medscape Nortriptyline
PubChem 4543
PubMed Nortriptyline
Kompas (Dutch) Nortriptyline
Wikipedia Nortriptyline

Switch medication from doxepin to nortriptyline.[2] [3]

Nietinrijdenbord.png Stop doxepin
  • Day 1: Decrease with about 25% of the original dose per 3 days.
Eenrichtingbord.png Start nortriptyline
  • No wash-out period is needed.
  • Day 1: Increase with about 25% of target dose per 3 days.
Infobord.png More information
  • Both drugs are a TCA with anticholinergic properties, so a switch to a relatively high starting dose can be made.
  1. 1.0 1.1 1.2 1.3 1.4 KNMP; Informatorium Medicamentorum 2023; Monografie "doxepine" (Dutch)
  2. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  3. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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