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Bupropion-paroxetine

42 bytes removed, 15:31, 7 October 2015

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| to = paroxetine

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* Gradually reduce dosage of bupropion to a maximum of 150 mg/ day. * When a dosage of 150 mg/day is reached, stop administration.{{StopBupropion1}}

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* ''' Day 2: ''' Start paroxetine in normal dosage of 20 mg/day.

* ''' After 3 weeks:''' If necessary increase dosage gradually to 30-50 mg/day.

| info =

* No wash-out period is needed.

* Start paroxetine the next day in normal dosage of 20 mg/day.

~~| info =~~

* Bupropion slows the metabolism of paroxetine by CYP2D6.

* Bupropion and its metabolites have long elimination times, so plasma concentrations will reduce gradually.

* {{2D6NRI}}

~~{{review}}~~

}}

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