Difference between revisions of "Paliperidone ER-Risperidone"

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(Created page with "<big><span style="color:#ff0000"> * This switch is intended for paliperidone long acting (Xeplion®, 30 days) </span></big> {{Drugswitch | from = Paliperidone LA | to = Risp...")
 
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{{Drugswitch  
 
{{Drugswitch  
 
| from = Paliperidone LA
 
| from = Paliperidone LA
| to = Risperidone
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| to = Risperidone<ref> A. Risselada, Switchen van en naar depotantipsychotica - een update; Psyfar, june 2022 nummer 2 </ref>
 
| stop = {{Lastinjection}}
 
| stop = {{Lastinjection}}
| start = {{Startafer30daysstandard}}
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| start = {{StartOral afterDepot}
 
| info = {{caveQT}}
 
| info = {{caveQT}}
| view = Stopdepotstartafter30days.png
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* the T<sub>1/2</sub> of a monthly paliperidon depot is approximately '''25-49 days'''.<ref> KNMP Kennisbank, informatorium medicamentorum: Paliperidon</ref>
 
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Revision as of 14:21, 20 February 2025

* This switch is intended for paliperidone long acting (Xeplion®, 30 days)

{{Drugswitch | from = Paliperidone LA | to = Risperidone[1] | stop =

  • Day 1: Last depot injection

| start = {{StartOral afterDepot} | info =

  • During this switch you could monitor ECG, especially in patients prone to QT-conduction problems.
  • There is a possibility of QT interval prolongation.[2]
  • the T1/2 of a monthly paliperidon depot is approximately 25-49 days.[3]

}}

  1. A. Risselada, Switchen van en naar depotantipsychotica - een update; Psyfar, june 2022 nummer 2
  2. Stöllberger C, Huber JO, Finsterer J, Antipsychotic drugs and QT prolongation. Int Clin Psychopharmacol. 2005 Sep;20(5):243-51.
  3. KNMP Kennisbank, informatorium medicamentorum: Paliperidon