Difference between revisions of "Moclobemide-fluvoxamine"

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(Created page with '{{Drugswitch | from = moclobemide | to = fluvoxamine | stop = * Gradually reduce dosage of moclobemide to a maximum of 300 mg/ day. * When a dosage of 300 mg/day is reached, ...')
 
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| to = fluvoxamine
 
| to = fluvoxamine
 
| stop =  
 
| stop =  
* Gradually reduce dosage of moclobemide to a maximum of 300 mg/ day.  
+
* '''Before day 0:''' gradually reduce dosage of moclobemide to a maximum of 300 mg/day.  
* When a dosage of 300 mg/day is reached, stop administration.
+
* '''Day 1:''' reduce the dosage of moclobemide to 150 mg/day.
 +
* '''Day 8:''' stop administration of moclobemide.
 
| start =   
 
| start =   
* '''Day 1-2:''' a wash-out period of two days is necessary.  
+
* '''Day 8-9:''' a wash-out period of two days is necessary.  
* '''Day 3:''' start fluvoxamine after this period in a normal dosage of 50 mg/day.}}
+
* '''Day 10:''' start fluvoxamine after this period in a normal dosage of 50 mg/day.}}

Revision as of 15:12, 7 May 2009

Moclobemide
Type Antidepressant
Group MAO-I
links
Medscape Moclobemide
PubChem 4235
PubMed Moclobemide
Kompas (Dutch) Moclobemide
Wikipedia Moclobemide
Fluvoxamine
Type Antidepressant
Group SSRI
links
Medscape Fluvoxamine
PubChem 5324346
PubMed Fluvoxamine
Kompas (Dutch) Fluvoxamine
Wikipedia Fluvoxamine

Switch medication from moclobemide to fluvoxamine.[1] [2]

Nietinrijdenbord.png Stop moclobemide
  • Before day 0: gradually reduce dosage of moclobemide to a maximum of 300 mg/day.
  • Day 1: reduce the dosage of moclobemide to 150 mg/day.
  • Day 8: stop administration of moclobemide.
Eenrichtingbord.png Start fluvoxamine
  • Day 8-9: a wash-out period of two days is necessary.
  • Day 10: start fluvoxamine after this period in a normal dosage of 50 mg/day.


  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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