Difference between revisions of "Mirtazapine-tranylcypromine"
From Psychiatrienet
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* '''Day 8:''' stop administration of mirtazapine. | * '''Day 8:''' stop administration of mirtazapine. | ||
| start = | | start = | ||
| − | * '''Day 8-21:''' a wash-out period of | + | * '''Day 8-21:''' a wash-out period of two weeks is necessary. |
* '''Day 22:''' start administration of tranylcypromine in a dosage of 20 mg/day for one week. | * '''Day 22:''' start administration of tranylcypromine in a dosage of 20 mg/day for one week. | ||
* '''Day 29:''' after this week the dosage of tranylcypromine can be increased if necessary. }} | * '''Day 29:''' after this week the dosage of tranylcypromine can be increased if necessary. }} | ||
Revision as of 15:58, 11 May 2009
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Switch medication from mirtazapine to tranylcypromine.[1] [2]
Stop mirtazapine - Day 0: gradually reduce dosage of mirtazapine to a maximum of 30 mg/ day.
- Day 1: reduce a dosage of 30 mg/day to 15 mg/day.
- Day 8: stop administration of mirtazapine.
Start tranylcypromine- Day 8-21: a wash-out period of two weeks is necessary.
- Day 22: start administration of tranylcypromine in a dosage of 20 mg/day for one week.
- Day 29: after this week the dosage of tranylcypromine can be increased if necessary.
- ↑ Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
- ↑ Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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