Difference between revisions of "Duloxetine-mianserine"

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* '''Day 0:''' gradually reduce dosage of duloxetine to a maximum of 60 mg/ day.
 
* '''Day 0:''' gradually reduce dosage of duloxetine to a maximum of 60 mg/ day.
 
* '''Day 1:''' reduce a dosage of 60 mg/day to 30 mg/day.
 
* '''Day 1:''' reduce a dosage of 60 mg/day to 30 mg/day.
 +
* '''Day 8:''' stop administration of duloxetine.
 
| start =   
 
| start =   
* '''Day 1:''' simultaneously start mianserine in a low dosage of 30 mg/day.
+
* '''Day 8:''' start mianserine in a low dosage of 30 mg/day.
* '''Day 8:''' stop administration of duloxetine and continue with mianserine only. }}
+
* '''Day 15:''' increase mianserine.
 +
}}

Revision as of 08:17, 4 August 2009

Duloxetine
Type Antidepressant
Group SNRI
links
Medscape Duloxetine
PubChem 60835
PubMed Duloxetine
Kompas (Dutch) Duloxetine
Wikipedia Duloxetine
Mianserine
Type Antidepressant
Group other
links
PubChem 4184
PubMed Mianserine
Kompas (Dutch) Mianserine
Wikipedia Mianserine

Switch medication from duloxetine to mianserine.[1] [2]

Nietinrijdenbord.png Stop duloxetine
  • Day 0: gradually reduce dosage of duloxetine to a maximum of 60 mg/ day.
  • Day 1: reduce a dosage of 60 mg/day to 30 mg/day.
  • Day 8: stop administration of duloxetine.
Eenrichtingbord.png Start mianserine
  • Day 8: start mianserine in a low dosage of 30 mg/day.
  • Day 15: increase mianserine.


  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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