Difference between revisions of "Citalopram-maprotiline"

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(Created page with '{{Drugswitch | from = citalopram | to = imipramine | stop = * Day 0: gradually reduce dosage of citalopram/escitalopram to a maximum of 20 mg/day resp. 10 mg/day, when this dosa...')
 
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* Day 0: gradually reduce dosage of citalopram/escitalopram to a maximum of 20 mg/day resp. 10 mg/day, when this dosage is respectively > 20 mg/day and > 10 mg/day.  
 
* Day 0: gradually reduce dosage of citalopram/escitalopram to a maximum of 20 mg/day resp. 10 mg/day, when this dosage is respectively > 20 mg/day and > 10 mg/day.  
 
* Day 1: Reduce dosage of citalopram/escitalopram to a maximum of 10 mg/day resp. 5 mg/day.  
 
* Day 1: Reduce dosage of citalopram/escitalopram to a maximum of 10 mg/day resp. 5 mg/day.  
* Day 8: stop administration of citalopram/escitalopram.
 
 
| start =  
 
| start =  
* Day 8: no wash-out period is needed. Start administration of imipramine in a low dosage of 25-75 mg/day.  
+
* Day 1: simultaneously start administration of maprotiline in a normal dosage of 25-75 mg/day.
* Start low, go slow!
+
* Day 8: stop administration of citalopram/escitalopram and continue administration of maprotiline only.
 
| info =  
 
| info =  
 +
* “Start low, go slow” for maprotiline is not required, but caution is necessary.
 
* The same applies to [[escitalopram]].
 
* The same applies to [[escitalopram]].
 
}}
 
}}

Revision as of 13:16, 1 May 2009

Citalopram
Type Antidepressant
Group SSRI
links
ATC-code N06AB04
Medscape Citalopram
PubChem 2771
PubMed Citalopram
Kompas (Dutch) citalopram
Wikipedia citalopram
Imipramine
Type Antidepressant
Group TCA
links
Medscape Imipramine
PubChem 3696
PubMed Imipramine
Kompas (Dutch) Imipramine
Wikipedia Imipramine

Switch medication from citalopram to imipramine.[1] [2]

Nietinrijdenbord.png Stop citalopram
  • Day 0: gradually reduce dosage of citalopram/escitalopram to a maximum of 20 mg/day resp. 10 mg/day, when this dosage is respectively > 20 mg/day and > 10 mg/day.
  • Day 1: Reduce dosage of citalopram/escitalopram to a maximum of 10 mg/day resp. 5 mg/day.
Eenrichtingbord.png Start imipramine
  • Day 1: simultaneously start administration of maprotiline in a normal dosage of 25-75 mg/day.
  • Day 8: stop administration of citalopram/escitalopram and continue administration of maprotiline only.
Infobord.png More information
  • “Start low, go slow” for maprotiline is not required, but caution is necessary.
  • The same applies to escitalopram.
  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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