Difference between revisions of "Risperidone LA-Rest AP"

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Latest revision as of 15:48, 26 August 2009

Risperidone
long acting
Type Antipsychotic
Group Atypical AP
links
Medscape Risperidone
PubChem 5073
PubMed Risperidone
Kompas (Dutch) Risperidone
Wikipedia Risperidone
Rest anti-psychotics

Chlorprothixene
Flupentixol
Loxapine
Pericyazine
Perphenazine
Trifluoperazine
Ziprasidone
Zuclopenthixol

Switch medication from Risperidone_LA to Rest AP.[1] [2]

Nietinrijdenbord.png Stop Risperidone_LA
  • Day 1: Last depot injection
Eenrichtingbord.png Start Rest AP
  • Day 35-38: approx. 25% of target dose
  • Day 39-42: approx. 50% of target dose
  • Day 43-46: approx. 75% of target dose
  • Day 47: target dose
Infobord.png More information
  • During this switch you could monitor ECG, especially in patients prone to QT-conduction problems.
  • There is a possibility of QT interval prolongation.[3]
    StopRisperLAStartOral.jpg
Nietinrijdenbord.png — Risperidone_LA
Eenrichtingbord.png — Rest AP


  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
  3. Stöllberger C, Huber JO, Finsterer J, Antipsychotic drugs and QT prolongation. Int Clin Psychopharmacol. 2005 Sep;20(5):243-51.
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