Difference between revisions of "Template:Switch-to-(9OH-)risperidone"
From Psychiatrienet
| Line 6: | Line 6: | ||
* '''Day 30:''' stop oral risperidone (or oral paliperidone) and administer paliperidone-LA: see this switch in the main cross table. | * '''Day 30:''' stop oral risperidone (or oral paliperidone) and administer paliperidone-LA: see this switch in the main cross table. | ||
| − | Oral risperidone has better and more stable bioavailability properties than oral 9-OH-risperidone=paliperidone. Food | + | Oral risperidone has better and more stable bioavailability properties than oral 9-OH-risperidone=paliperidone. Food increases the absorption with 50-60% of the latter. |
Revision as of 15:23, 6 May 2011
There are 2 switch possibities:
Number 1 (the general approach):
- Day 1: Switch to oral risperidone (or oral paliperidone): see this switch in the main cross table.
- Day 1-29: Maintain on oral risperidone (or oral paliperidone) and examine the effects.
- Day 30: stop oral risperidone (or oral paliperidone) and administer paliperidone-LA: see this switch in the main cross table.
Oral risperidone has better and more stable bioavailability properties than oral 9-OH-risperidone=paliperidone. Food increases the absorption with 50-60% of the latter.
Number 2 (if a patient in the past reacted well on risperidon or paliperidone=9-OH-risperidone):
