Difference between revisions of "Vortioxetine-escitalopram"
From Psychiatrienet
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* '''Day 1:''' reduce dosage of vortioxetine to 5 mg/day. | * '''Day 1:''' reduce dosage of vortioxetine to 5 mg/day. | ||
| − | * '''Day | + | * '''Day 8:''' stop administration of vortioxetine. |
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* No wash-out period is needed. | * No wash-out period is needed. | ||
| − | * | + | * '''Day 8:''' start escitalopram in a normal dosage of 10 mg/day. |
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* {{theorSS}} | * {{theorSS}} | ||
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Revision as of 11:57, 12 March 2015
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Switch medication from vortioxetine to escitalopram.[1] [2]
Stop vortioxetine - Day 1: reduce dosage of vortioxetine to 5 mg/day.
- Day 8: stop administration of vortioxetine.
Start escitalopram- No wash-out period is needed.
- Day 8: start escitalopram in a normal dosage of 10 mg/day.
More information- Occurrence of the serotonin syndrome is not likely, but theoretically possible, so caution is necessary.
- ↑ Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
- ↑ Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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