Difference between revisions of "Mirtazapine-paroxetine"
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Switch medication from mirtazapine to paroxetine.[1] [2]
Stop mirtazapine - Before day 1: Gradually reduce dosage of mirtazapine to a maximum of 30 mg/day, when this dosage is > 30 mg/day.
- Day 1: Reduce dosage of mirtazapine to 15 mg/day.
- Day 8: Stop administration of mirtazapine.
Start paroxetine- Day 2: Start paroxetine in normal dosage of 20 mg/day.
- After 3 weeks: If necessary increase dosage gradually to 30-50 mg/day.
- ↑ Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
- ↑ Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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