Difference between revisions of "Vortioxetine-moclobemide"
From Psychiatrienet
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| to = moclobemide | | to = moclobemide | ||
| stop = | | stop = | ||
| − | + | {{stopVortioxetine}} | |
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| start = | | start = | ||
| − | * '''Day 8- | + | * '''Day 8-23:''' a wash-out period of 2 weeks is necessary. |
| − | * '''Day | + | * '''Day 24:''' start administration of moclobemide in normal dosage of 300 mg/day. |
| caveat = {{caveSS}} | | caveat = {{caveSS}} | ||
| − | |||
}} | }} | ||
Revision as of 11:56, 4 November 2015
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Switch medication from vortioxetine to moclobemide.[1] [2]
Stop vortioxetine - Day 1: reduce dosage of vortioxetine to 5 mg/day.
- Day 8: stop administration of vortioxetine.
Start moclobemide- Day 8-23: a wash-out period of 2 weeks is necessary.
- Day 24: start administration of moclobemide in normal dosage of 300 mg/day.
Cave- Occurrence of the serotonin syndrome is possible without wash-out period.
- ↑ Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
- ↑ Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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