Difference between revisions of "Venlafaxine-amitriptyline"
From Psychiatrienet
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| to = amitriptyline | | to = amitriptyline | ||
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| − | {{ | + | {{stopVenlafaxine}} |
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| − | * '''Day | + | * '''Day 9:''' start administration of amitriptyline in a low dosage of 25 mg/day. |
| − | * '''Day | + | * '''Day 16:''' continue administration of amitriptyline in a dosage of 50 mg/day. |
| info = | | info = | ||
* “Start low, go slow” for amitriptyline, and caution with this switch is necessary. | * “Start low, go slow” for amitriptyline, and caution with this switch is necessary. | ||
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}} | }} | ||
Revision as of 13:20, 4 November 2015
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Switch medication from venlafaxine to amitriptyline.[1] [2]
Stop venlafaxine - Before day 1: gradually reduce dosage of venlafaxine to a maximum of 75 mg/ day.
- Day 1: reduce a dosage of 75 mg/day to 37,5 mg/day.
- Day 8: stop administration of venlafaxine.
Start amitriptyline- Day 9: start administration of amitriptyline in a low dosage of 25 mg/day.
- Day 16: continue administration of amitriptyline in a dosage of 50 mg/day.
More information- “Start low, go slow” for amitriptyline, and caution with this switch is necessary.
- ↑ Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
- ↑ Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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