Venlafaxine-trazodone
From Psychiatrienet
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Switch medication from venlafaxine to trazodone.[1] [2]
Stop venlafaxine - Gradually reduce dosage of venlafaxine to a maximum of 75 mg/day, when this dosage is > 75 mg/day.
- When a dosage of 75 mg/day is reached, stop administration.
Start trazodone- Day 1: start administration of trazodone the next day in a dosage of 300 mg/day
- If necessary, increase dosage of trazodone to a maximum of 400 mg/day.
- ↑ Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
- ↑ Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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