Moclobemide-maprotiline
From Psychiatrienet
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Switch medication from moclobemide to maprotiline.[1] [2]
Stop moclobemide Administration of moclobemide can be stopped abruptly.
Start maprotiline- Day 1-2: a wash-out period of two days is necessary.
- Day 3: start maprotiline after this period in a normal dosage of 25-75 mg/day.
- “Start low, go slow” is not required, but caution is necessary.
- ↑ Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
- ↑ Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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