Fluvoxamine-trazodone
From Psychiatrienet
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Switch medication from fluvoxamine to trazodone.[1] [2]
Stop fluvoxamine {[stopFluvoxamine
- ↑ Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
- ↑ Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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- Day 9: start trazodone in dosage of 100-150 mg/day.
- Day 16: If necessary, increase the dosage of trazodone every 3-4 days with 50 mg to a maximum of 400 mg/day.
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- Occurrence of the serotonin syndrome is not likely, but theoretically possible, so caution is necessary.
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