Bupropion-tranylcypromine

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Bupropion
Type Antidepressant
Group other
links
ATC-code N06AX12
Medscape Bupropion
PubChem 444
PubMed Bupropion
Kompas (Dutch) Bupropion
Wikipedia Bupropion
Tranylcypromine
Type Antidepressant
Group MAO-I
links
Medscape Tranylcypromine
PubChem 5530
PubMed Tranylcypromine
Kompas (Dutch) Tranylcypromine
Wikipedia Tranylcypromine

Switch medication from bupropion to tranylcypromine.[1] [2]

Nietinrijdenbord.png Stop bupropion
  • Day 1: halve the dose if possible otherwise stop.
  • Day 7: stop.
Eenrichtingbord.png Start tranylcypromine
  • Day 1: Start and increase the dose with about 25% of the target dose every 3 days.


  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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