Paroxetine-mianserine

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paroxetine
Type Antidepressant
Group SSRI
links
Medscape paroxetine
PubChem 43815
PubMed paroxetine
Kompas (Dutch) paroxetine
Wikipedia paroxetine
Mianserine
Type Antidepressant
Group other
links
PubChem 4184
PubMed Mianserine
Kompas (Dutch) Mianserine
Wikipedia Mianserine

Switch medication from paroxetine to mianserine.[1] [2]

Nietinrijdenbord.png Stop paroxetine
  • Gradually reduce dosage of paroxetine to a maximum of 20 mg/ day, when this dosage is > 20 mg/day.
Eenrichtingbord.png Start mianserine
  • Day 1: reduce paroxetine to a dosage of 10 mg/day and start administration of mianserine in a low dosage of 30 mg/day for one week.
  • Day 8: stop administration of paroxetine and continue administration of mianserine only.


  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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