* Agomelatine can be stopped abruptly for every dosage. ''' Day 1: ''' Stop agomelatine
| start =
{{Startmoclo}}
| info =
* A wash-out period is not necessary.
* Start administration of moclobemide the next day in a normal dosage of 300 mg/day.
<ref name="agoswitch"> {{Pubmed|20196187|McAllister-Williams RH et al. The use of antidepressants in clinical practice: focus on agomelatine. Hum Psychopharmacol. 2010 Mar 1;25(2):95-102}}</ref>