* '''Day 0:''' gradually reduce dosage of amitriptyline to a maximum of 50-100 mg/day, when this dosage is > 100 mg/day.* '''Day 1-7:''' reduce dosage of amitriptyline to 25-50 mg/day.* '''Day 8:''' stop administration of amitriptyline. {{TCAdecrease25p3d}}| start = {{StartAntidepressant}}* '''Day 8-14:''' a wash-out period of one week is necessary.| info =* '''Day 15:''' start administration of Safe target dose duloxetine in a normal dosage of = 60 mg/day.}}
